Publications
- Annotaded publication list:
- Most cited papers:
Publications 2010-2024
To go directly to a specific year, please click on the year here: 2022, 2021, 2020, 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, 2011, 2010
2024
Alessandro Fiorenzano, Petter Storm, Edoardo Sozzi, Andreas Bruzelius, Sara Corsi, Janko Kajtez, Janitha Mudannayake, Jenny Nelander, Bengt Mattsson, Malin Åkerblom, Tomas Björklund, Anders Björklund, Malin Parmar
TARGET-seq: Linking single-cell transcriptomics of human dopaminergic neurons with their target specificity OPEN ACCESS
Proc Natl Acad Sci U S A. 2024 Nov 19
Anders Björklund∗ and Bengt Mattsson
The AAV-α-Synuclein Model of Parkinson’s Disease: An Update OPEN ACCESS
Journal of Parkinson's Disease, Published: 19 July 2024
Roger A Barker, Anders Björklund, Malin Parmar
The history and status of dopamine cell therapies for Parkinson’s diseaseOPEN ACCESS
BioEssays. 26 July 2024.
Anders Björklund, Roger A Barker
The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson's disease OPEN ACCESS
Brain. 2024 Jan 27
2023
Agnete Kirkeby, Jenny Nelander, Deirdre B. Hoban, Nina Rogelius, Hjalmar Bjartmarz, Novo Nordisk Cell Therapy R&D, Petter Storm, Alessandro Fiorenzano, Andrew F. Adler, Shelby Vale, Janitha Mudannayake, Yu Zhang, Tiago Cardoso, Bengt Mattsson, Anne M. Landau, Andreas N. Glud, Jens C. Sørensen, Thea P. Lillethorup, Mark Lowdell, Carla Carvalho, Owen Bain, Trinette van Vliet, Olle Lindvall, Anders Björklund, Bronwen Harry, Emma Cutting, Håkan Widner, Gesine Paul, Roger A. Barker, and Malin Parmar
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson’s disease, STEM-PDOPEN ACCESS
Cell Stem Cell. Volume 30, Issue 10, 5 October 2023
Roger A. Barker, Anders Björklund
Restorative cell and gene therapies for Parkinson’s disease
Handbook of Clinical Neurology, Vol. 193 (3rd series) Precision Medicine in Neurodegenerative Disorders, Part II
2022
Anders Björklund, Fredrik Nilsson, Bengt Mattsson, Deirdre B Hoban, Malin Parmar
A Combined α-Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System OPEN ACCESS
J Parkinsons Dis, 2022 Sep 26
2021
Anders Björklund, Bastiaan R. Bloem, Patrik Brundin and Howard Federoff
Repairing the Parkinson Brain
Journal of Parkinson's Disease, vol. 11, 22 September 2021
Malin Parmar, Anders Björklund, Tomas Björklund
In vivo conversion of dopamine neurons in mouse models of Parkinson’s disease — a future approach for regenerative therapy?
Current Opinion in Genetics & Development, Volume 70, October 2021, Pages 76-82
Roger A Barker, Anders Björklund, Steven J Frucht, Clive N Svendsen
Stem Derived Dopamine Neurons: Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?
Journal of Parkinson's Disease, 26 July 2021
Anders Björklund
GDNF Therapy: Can We Make It Work?
Journal of Parkinson's Disease, 30 April 2021
Anders Björklund, Malin Parmar
Dopamine Cell Therapy: From Cell Replacement to Circuitry Repair OPEN ACCESS
Journal of Parkinson's Disease, 2021 March 29
Shelby Shrigley, Fredrik Nilsson, Bengt Mattsson, Alessandro Fiorenzano, Janitha Mudannayake, Andreas Bruzelius, Daniella Rylander Ottosson, Anders Björklund, Deirdre B Hoban, Malin Parmar
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease OPEN ACCESS
Journal of Parkinson's Disease, 13 April 2021
Roussakis AA, Zeng Z, Lao-Kaim NP, Martin-Bastida A, Piccini P, TRANSEURO consortium (incl. Björklund A, Nelander-Wahlestedt J, Parmar M)
Parkinson's disease laterality: a 11 C-PE2I PET imaging study OPEN ACCESS
J Neurol. 2021
2020
Malin Parmar, Anders Björklund
From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells
CellStemCell, 2020-07-27
Scheggi S, Rossi F, Corsi S, Fanni S, Tronci E, Ludovica C, Vargiu R, Gambarana C, Muñoz A, Stancampiano R, Bjorklund A, Carta M
BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia
Journal of Parkinson's Disease, 08 July 2020
Barker R A, Björklund A, Gash D M, Whone A, Van Laar A, Kordower J H, Bankiewicz K, Kieburtz K, Saarma M, Booms S, Huttunen H J, Kells A P, Fiandaca M S, Stoessl A. J, Eidelberg D, Federoff H, Voutilainen M H, Dexter D T, Eberling J, Brundin P, Isaacs L, Mursaleen L, Bresolin E, Carroll C, Coles A, Fiske B, Matthews H, Lungu C, Wyse R K, Stott S, Lang A E.
GDNF and Parkinson’s Disease: Where Next? A Summary from a Recent Workshop OPEN ACCESS
Journal of Parkinson’s Disease 10 (2020)
Barker, Roger A., Björklund, Anders
Animal Models of Parkinson’s Disease: Are They Useful or Not? OPEN ACCESS
Journal of Parkinson's Disease, 21 July 2020
Hoban D B, Shrigley S, Mattsson B, Breger L S, Jarl U, Cardoso T, Nelander Wahlestedt J, Luk K C, Björklund A, Parmar M
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD
PNAS. 15 June 2020.
Anders Björklund, Malin Parmar
Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair: 40 Years in Perspective OPEN ACCESS
Front. Cell. Neurosci., 29 May 2020
Anders Bjorklund, Angela Cenci-Nilsson (Serial Volume Editors)
Recent Advances in Parkinson's Disease, Volume 252, 1st Edition
Imprint: Elsevier. Published Date: 2nd April 2020
Cenci MA, Björklund A.
Animal models for preclinical Parkinson´s research: An update and critical appraisal.
Progress in Brain Research 252:27-59, 2020
Adler AF, Björklund A, Parmar M.Open Access
Transsynaptic tracing and its emerging use to assess graft-reconstructed neural circuits. OPEN ACCESS
Stem Cells. 2020 Feb 26.
2019
Adler A. F., Cardoso T., Nolbrant S., Mattsson B., Hoban D.B., Jarl U., Nelander Wahlestedt J., Grealish Sh., Björklund A., Parmar M.
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson’s Disease OPEN ACCESS
Cell Reports. VOLUME 28, ISSUE 13, P3462-3473.E5, September 24, 2019
Barker RA; TRANSEURO consortium.
Designing stem-cell-based dopamine cell replacement trials for Parkinson's disease.
Nat Med. July 1st 2019.
Rosenblad C, Li Q, Pioli EY, Dovero S, Antunes ASLM, Agúndez L, Bardelli M, Linden RM, Henckaerts E, Björklund A, Bezard E, Björklund T.
Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease. OPEN ACCESS
Brain. 2019 Jun 26
Anders Björklund, Stephen B. Dunnett.
The Amphetamine Induced Rotation Test: A Re-Assessment of Its Use as a Tool to Monitor Motor Impairment and Functional Recovery in Rodent Models of Parkinson’s Disease. OPEN ACCESS
Journal of Parkinson’s Disease 9 (2019) 17–29
2018
Faustini G, Longhena F, Varanita T, Bubacco L, Pizzi M, Missale C, Benfenati F, Björklund A, Spano P, Bellucci A
Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson's disease.
Acta Neuropathol. 2018 Jul 25
Cardoso T, Adler AF, Mattsson B, Hoban DB, Nolbrant S, Wahlestedt JN, Kirkeby A, Grealish S, Björklund A, Parmar M.
Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats. OPEN ACCESS
J Comp Neurol. 2018 Jul 14.
The History of Neuroscience in Autobiography, Volume 10, sid. 78-120.
Edited by Thomas D. Albright and Larry R. Squire
ISBN: 978-0-916110-10-9
Carta M, Björklund A
The serotonergic system in L-DOPA-induced dyskinesia: pre-clinical evidence and clinical perspective
Journal of Neural Transmission, February 26th, 2018
2017
Thakur P, Breger LS, Lundblad M, Wan OW, Mattsson B, Luk KC, Lee VMY, Trojanowski JQ, Björklund A
Modeling Parkinson's disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain.
Proc Natl Acad Sci U S A. 2017 Sep 12
Tronci E, Napolitano F, Muñoz A, Fidalgo C, Rossi F, Björklund A, Usiello A, Carta M.
BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to l-DOPA-induced dyskinesia in 6-OHDA-lesioned rats.
Exp Neurol. 2017 Jul 27
Stephen B. Dunnett and Anders Björklund (Volume Editors)
Functional Neural Transplantation IV, Volume 231
Progress in Brain Research, Volume 231 (2017): Translation to Clinical Application, Part B
Dunnett S.B., Björklund A
Chapter 1 – Mechanisms and use of neural transplants for brain repair
Progress in Brain Research, Functional Neural Transplantation IV — Translation to Clinical Application, Part A, Volume 230, 2017, Pages 1–51
Stephen B. Dunnett and Anders Björklund (Volume Editors)
Björklund A, Lindvall O
Replacing Dopamine Neurons in Parkinson’s Disease: How did it happen? OPEN ACCESS
Journal of Parkinson’s Disease 7 (2017) S23–S33
2016
Wan OW, Shin E, Mattsson B, Caudal D, Svenningsson P, Björklund A
α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter OPEN ACCESS
Sci Rep. 2016 May 23
Barker RA, Parmar M, Kirkeby A, Björklund A, Thompson L, Brundin P.
Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016? OPEN ACCESS
J Parkinsons Dis. 2016;6(1):57-63.
Li W, Englund E, Widner H, Mattsson B, van Westen D, Lätt J, Rehncrona S, Brundin P, Björklund A, Lindvall O, Li JY
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain. OPEN ACCESS
Proc Natl Acad Sci U S A. 2016 May 2.
Alvarsson A, Caudal D, Björklund A, Svenningsson P.
Emotional memory impairments induced by AAV-mediated overexpression of human α-synuclein in dopaminergic neurons of the ventral tegmental area.
Behav Brain Res. 2016 Jan 1;296:129-33.
2015
Tamburrino A, Churchill MJ, Wan OW, Colino-Sanguino Y, Ippolito R, Bergstrand S, Wolf DA, Herz NJ, Sconce MD, Björklund A, Meshul CK, Decressac M
Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson’s disease OPEN ACCESS
Acta Neuropathol Commun. 2015 Dec 14;3(1):84.
Volakakis N, Tiklova K,Decressac M, Papathanou M, Mattsson B, Gillberg L, Nobre A, Björklund A, Perlmann T
Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression
The Journal of Neuroscience, October 21, 2015
Caudal D, Alvarsson A, Björklund A, Svenningsson P
Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons
Exp Neurol. 2015 Sep 9
Tozzi A, de Iure A, Bagetta V, Tantucci M, Durante V, Quiroga-Varela A, Costa C, Di Filippo M, Ghiglieri V, Latagliata EC, Wegrzynowicz M, Decressac M, Giampà C, Dalley JW, Xia J, Gardoni F, Mellone M, El-Agnaf OM, Ardah MT, Puglisi-Allegra S, Björklund A, Spillantini MG, Picconi B, Calabresi P
Alpha-Synuclein Produces Early Behavioral Alterations Via Striatal Cholinergic Synaptic Dysfunction by Interacting with GluN2D N-Methyl-D-Aspartate Receptor Subunit.
Biol Psychiatry. 2015 Aug 20
Grealish S, Heuer A, Cardoso T, Kirkeby A, Jönsson M, Johansson J, Björklund A, Jakobsson J, Parmar M
Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons OPEN ACCESS
Stem Cell Reports. 2015 May 20
Thompson LH, Björklund A
Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells.
Neurobiol Dis. 2015 Apr 22; 79:28-40.
Bye CR, Jönsson ME, Björklund A, Parish CL, Thompson LH
Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors. OPEN ACCESS
Proc Natl Acad Sci U S A. 2015 Mar 9.
Kopra J, Vilenius C, Grealish Sh, Härma M-A, Varendi K, Jesse Lindholm J, Castrén E, Võikar V, Björklund A, Petteri Piepponen T, Saarma M, Andressoo J-O
GDNF is not required for catecholaminergic neuron survival in vivo
Nature Neuroscience 18,319–322(2015), Published online 24 February 2015
Smith R, Wu K, Hart T, Loane C, Brooks DJ, Björklund A, Odin P, Piccini P, Politis M
The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study
Neurobiol Aging. 2015 Jan 6.
Svenningsson P, Rosenblad C, af Edholm Arvidsson K, Wictorin K, Keywood C, Shankar B, Lowe DA, Björklund A, Widner H
Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study OPEN ACCESS
Brain a Journal of Neurology. First published online: 10 February 2015
2014
Grealish S, Diguet E, Kirkeby A, Mattsson B, Heuer A, Bramoulle Y, Van Camp N, Perrier A.L., Hantraye P, Björklund A, Parmar M
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease OPEN ACCESS
Cell Stem Cell, Volume 15, Issue 5, 6 November 2014, Pages 653–665
Shin E, Rogers J T, Devoto P, Björklund A, Carta M
Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease OPEN ACCESS
Experimental Neurology, Volume 257, July 2014, Pages 25-38
Shin E, Lisci C, Tronci E, Fidalgo C, Stancampiano R, Björklund A, Carta M.
The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation. OPEN ACCESS
Neurobiology of Disease, Volume 62, February 2014, Pages 233–240
2013
Kefalopoulou Z, Politis M, Piccini P, Mencacci N, Bhatia K, Jahanshahi M, Widner H, Rehncrona S, Brundin P, Björklund A, Lindvall O, Limousin P, Quinn N, Foltynie T.
Long-term Clinical Outcome of Fetal Cell Transplantation for Parkinson Disease: Two Case Reports. OPEN ACCESS
JAMA Neurology. 2013 Nov 11
Bézard E, Muñoz A, Tronci E, Pioli EY, Li Q, Porras G, Björklund A, Carta M.
Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia.
Neurosci Res. 2013 Oct 14
Decressac M, Björklund A
mTOR Inhibition Alleviates L-DOPAInduced Dyskinesia in Parkinsonian Rats
Journal of Parkinson's Disease. Volume 3, Number 1 / 2013
Decressac M, Volakakis N, Björklund A, Perlmann T
NURR1 in Parkinson disease-from pathogenesis to therapeutic potential
Nature Reviews Neurology. 2013 Oct 15th.
Decressac M, Björklund A
TFEB: Pathogenic role and therapeutic target in Parkinson disease OPEN ACCESS
Landes Bioscience, Published Online: May 22, 2013, Volume 9, Issue 8 August 2013
Decressac M, Mattsson B, Weikop P, Lundblad M, Jakobsson J, Björklund A
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
PNAS April 22, 2013
Decressac M, Björklund A
mTOR Inhibition Alleviates L-DOPA-Induced Dyskinesia in Parkinsonian Rats
Journal of Parkinson's Disease, Volume 3, Number 1 / 2013, pages 13-17
Torper O, Pfisterer U, Wolf DA, Pereira M, Lau S, Jakobsson J, Björklund A, Grealish S, Parmar M
Generation of induced neurons via direct conversion in vivo OPEN ACCESS
PNAS March 25, 2013
Bezard E, Tronci E, Pioli EY, Li Q, Porras G, Björklund A, Carta M.
Study of the Antidyskinetic Effect of Eltoprazine in Animal Models of Levodopa-Induced Dyskinesia. OPEN ACCESS
Mov Disord. 2013 Feb 6.
Bjorklund A, Kordower JH
Cell therapy for Parkinson's disease: what next? OPEN ACCESS
Mov Disord. 2013 Jan;28(1):110-5
Kordower JH, Bjorklund A
Trophic factor gene therapy for Parkinson's disease. OPEN ACCESS
Mov Disord. 2013 Jan;28(1):96-109.
Kadkhodaei B, Alvarsson A, Schintu N, Ramsköld D, Volakakis N, Joodmardi E, Yoshitake T, Kehr J, Decressac M, Björklund A, Sandberg R, Svenningsson P, Perlmann T.
Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons.
Proc Natl Acad Sci U S A. 2013 Jan 22.
Barker RA, Barrett J, Mason SL, Björklund A
Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease.
Lancet Neurol. 2013 Jan;12(1):84-91.
2012
Functional Neural Transplantation IV
Progress in Brain Research, Volume 201 (2012): Primary and Stem Cell Therapies for Brain Repair, Part II
Stephen B. Dunnett and Anders Björklund (Volume Editors)
Functional Neural Transplantation III
Progress in Brain Research, Volume 200 (2012): Primary and Stem Cell Therapies for Brain Repair, Part I
Stephen B. Dunnett and Anders Björklund (Volume Editors)
Chapter 1 - Introduction (part I)
Decressac M, Kadkhodaei B, Mattsson B, Laguna A, Perlmann T, Björklund A
α-Synuclein–Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons
Sci Transl Med 5 December 2012: Vol. 4, Issue 163, p. 163ra156.
Thompson L, Björklund A
Chapter 5 – Survival, differentiation, and connectivity of ventral mesencephalic dopamine neurons following transplantation
Progress in Brain Research, Volume 200, 2012, Pages 61–95.
Stephen B. Dunnett and Anders Björklund (Volume Editors)
Functional Neural Transplantation III — Primary and Stem Cell Therapies for Brain Repair, Part I
Decressac M, Barker R.A.
Neuropeptide Y and its role in CNS disease and repair
Experimental Neurology, Volume 238, Issue 2, December 2012, Pages 265–272.
Angot E, Steiner JA, Lema Tomé CM, Ekström P, Mattsson B, Björklund A, Brundin P.
Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo OPEN ACCESS
PLoS One. 2012;7(6):e39465. Epub 2012 Jun 21.
Shin E, Tronci E, Carta M
Role of Serotonin Neurons in L-DOPA- and Graft-Induced Dyskinesia in a Rat Model of Parkinson's Disease
Parkinson's Disease, Volume 2012 (2012), Accepted 10 April 2012
Shin E, Garcia J, Winkler C, Björklund A, Carta M.
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.
Neurobiol Dis. 2012 Apr 12.
Parmar M, Björklund A
Generation of Transplantable Striatal Projection Neurons from Human ESCs
Cell Stem Cell. Volume 10, Issue 4, 6 April 2012, Pages 349–350.
Politis M, Wu K, Loane C, Quinn N P, Brooks D J, Oertel W H, Björklund A, Lindvall O, Piccini P
Serotonin Neuron Loss and Nonmotor Symptoms Continue in Parkinson’s Patients Treated with Dopamine Grafts.
Science Translational Medicine. 4 April 2012 4:128ra41.
Tronci E, Shin E, Björklund A, Carta M
Amphetamine-induced rotation and l-DOPA-induced dyskinesia in the rat 6-OHDA model: A correlation study.
Neuroscience Research. 16 March 2012.
Decressac M, Mattsson B, Björklund A.
Comparison of the behavioural and histological characteristics of the 6-OHDA and α-synuclein rat models of Parkinson's disease.
Experimental Neurology. 25 February 2012.
Lundblad M, Decressac M, Mattsson B, Björklund A.
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons. OPEN ACCESS
Proc Natl Acad Sci USA. 2012 Feb 6.
2011
Decressac M, Mattsson B, Lundblad M, Weikop P, Björklund A.
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons
Neurobiology of Disease. 11 December 2011.
Lindvall O, Björklund A.
Cell Therapeutics in Parkinson's Disease.
Neurotherapeutics. 2011 Sep 9.
Decressac M, Ulusoy A, Mattsson B, Georgievska B, Romero-Ramos M, Kirik D, Björklund A.
GDNF fails to exert neuroprotection in a rat {alpha}-synuclein model of Parkinson's disease.
Brain. 2011 Jun 28.
Pfisterer U, Kirkeby A, Torper O, Wood J, Nelander J, Dufour A, Björklund A, Lindvall O, Jakobsson J, Parmar M.
Direct conversion of human fibroblasts to dopaminergic neurons.
Proc Natl Acad Sci U S A. 2011 Jun 6.
Politis M, Oertel WH, Wu K, Quinn NP, Pogarell O, Brooks DJ, Bjorklund A, Lindvall O, Piccini P.
Graft-induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio.
Mov Disord. 2011 May 24. doi: 10.1002/mds.23743.
Björklund A, Björklund T.
Gene therapy for Parkinson's disease shows promise.
Sci Transl Med. 2011 Apr 20;3(79):79ed1.
2010
Politis M, Wu K, Loane C, Quinn NP, Brooks DJ, Rehncrona S, Bjorklund A, Lindvall O, Piccini P.
Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants.
Sci Transl Med. 2010 Jun 30;2(38):38-46.
Denham M, Thompson LH, Leung J, Pébay A, Björklund A, Dottori M.
Gli is an inducing factor in generating floor plate progenitor cells from human embryonic stem cells.
Stem Cells. Oct;28(10):1805-15.
Sachdeva R, Jönsson ME, Nelander J, Kirkeby A, Guibentif C, Gentner B, Naldini L, Björklund A, Parmar M, Jakobsson J.
Tracking differentiating progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors.
Proc Natl Acad Sci U S A. Jun 22;107(25):11602-7. Epub 2010 Jun 7.
Recent Advances in Parkinson´s Disease Progress in Brain Research
Volume 183 (2010): Part I: Basic research
Anders Björklund and Angela Cenci-Nilsson (Volume Editors)
Ulusoy A, Decressac M, Kirik D, Björklund A.
Viral vector mediated expression of a-synuclein as a progressive model of Parkinson´s Disease.
Progress in Brain Research, Volume 184 (2010): Part II: Translational and clinical research
Anders Björklund and Angela Cenci-Nilsson (Volume Editors)
Lane EL, Björklund A, Dunnett SB, Winkler C.
Neural grafting in Parkinson's disease: unraveling the mechanisms underlying graft-induced dyskinesia.
Prog Brain Res. 2010;184:295-309.
Carta M, Carlsson T, Muñoz A, Kirik D, Björklund A.
Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease.
Mov Disord. 2010;25 Suppl 1:S174-9.
Grealish S, Mattsson B, Draxler P, Björklund A.
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease.
Eur J Neurosci. 2010 Jun 1.
Li JY, Englund E, Widner H, Rehncrona S, Björklund A, Lindvall O, Brundin P.
Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease
Mov Disord. 2010 Mar 2.
Grealish S, Jönsson ME, Li M, Kirik D, Björklund A, Thompson LH.
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease.
Brain. 2010 Feb;133(Pt 2):482-95.